Laminin–A glycoprotein from basement membranes.
…, PG Robey, SI Rennard, JM Foidart, GR Martin - Journal of biological …, 1979 - ASBMB
We have isolated a large noncollagenous glycoprotein, laminin, from a mouse tumor that
produces basement membrane. The protein consists of at least two polypeptide chains (Mr = …
produces basement membrane. The protein consists of at least two polypeptide chains (Mr = …
Isolation and characterization of type IV procollagen, laminin, and heparan sulfate proteoglycan from the EHS sarcoma
… Liotta, Pamela Gehron Robey, Karl Tryggvason, and George R. Martin abstract: We have
studied the extractability of type IV collagen, laminin, and heparan sulfate proteoglycan from …
studied the extractability of type IV collagen, laminin, and heparan sulfate proteoglycan from …
Extension of murine life span by overexpression of catalase targeted to mitochondria
SE Schriner, NJ Linford, GM Martin, P Treuting… - science, 2005 - science.org
To determine the role of reactive oxygen species in mammalian longevity, we generated
transgenic mice that overexpress human catalase localized to the peroxisome, the nucleus, or …
transgenic mice that overexpress human catalase localized to the peroxisome, the nucleus, or …
Positional cloning of the Werner's syndrome gene
Werner's syndrome (WS) is an inherited disease with clinical symptoms resembling premature
aging. Early susceptibility to a number of major age-related diseases is a key feature of …
aging. Early susceptibility to a number of major age-related diseases is a key feature of …
Matrigel: basement membrane matrix with biological activity
HK Kleinman, GR Martin - Seminars in cancer biology, 2005 - Elsevier
The basement membrane extracellular matrix contacts epithelial, endothelial, fat and
smooth muscle cells. Because this extracellular matrix is so thin, it had been hard to study its …
smooth muscle cells. Because this extracellular matrix is so thin, it had been hard to study its …
Basement membrane complexes with biological activity
…, VL Star, FB Cannon, GW Laurie, GR Martin - Biochemistry, 1986 - ACS Publications
We have studied the reconstitution of basement membrane molecules from extracts prepared
from the basement membrane of the EHS tumor. Under physiological conditions and in the …
from the basement membrane of the EHS tumor. Under physiological conditions and in the …
Osteonectin, a bone-specific protein linking mineral to collagen
…, SW Whitson, KM Conn, ML McGarvey, GR Martin - Cell, 1981 - Elsevier
Osteonectin is a 32,000 dalton bone-specific protein that binds selectively to both hydroxyapatite
and collagen. When osteonectin is bound to insolubilized type I collagen, the resultant …
and collagen. When osteonectin is bound to insolubilized type I collagen, the resultant …
Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures.
Y Kubota, HK Kleinman, GR Martin… - The Journal of cell …, 1988 - rupress.org
We have defined a signal responsible for the morphological differentiation of human
umbilical vein and human dermal microvascular endothelial cells in vitro. We find that human …
umbilical vein and human dermal microvascular endothelial cells in vitro. We find that human …
[HTML][HTML] Role of collagenous matrices in the adhesion and growth of cells.
HK Kleinman, RJ Klebe, GR Martin - The Journal of cell biology, 1981 - ncbi.nlm.nih.gov
It has long been appreciated that, for many types of cells, attachment to a substrate is required
for their replication. Collagen substrates enhance the growth (64, 70, 109, 238) as well as …
for their replication. Collagen substrates enhance the growth (64, 70, 109, 238) as well as …
Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14
Linkage analysis was used to search the genome for chromosomal regions harboring familial
Alzheimer's disease genes. Markers on chromosome 14 gave highly significant positive …
Alzheimer's disease genes. Markers on chromosome 14 gave highly significant positive …