A gene expression signature that defines breast cancer metastases
…, LA Field, C Heckman, J Kane, JA Hooke… - Clinical & experimental …, 2009 - Springer
The most important predictor of prognosis in breast cancer is lymph node status, yet little is
known about molecular changes associated with lymph node metastasis. Here, gene …
known about molecular changes associated with lymph node metastasis. Here, gene …
[HTML][HTML] Loss of nuclear localized and tyrosine phosphorylated Stat5 in breast cancer predicts poor clinical outcome and increased risk of antiestrogen therapy failure
…, N Yang, AL Rosenberg, JA Hooke… - Journal of clinical …, 2011 - ncbi.nlm.nih.gov
Purpose To investigate nuclear localized and tyrosine phosphorylated Stat5 (Nuc-pYStat5)
as a marker of prognosis in node-negative breast cancer and as a predictor of response to …
as a marker of prognosis in node-negative breast cancer and as a predictor of response to …
Prolactin suppresses a progestin-induced CK5-positive cell population in luminal breast cancer through inhibition of progestin-driven BCL6 expression
…, I Chervoneva, T Hyslop, AJ Kovatich, JA Hooke… - Oncogene, 2014 - nature.com
Prolactin controls the development and function of milk-producing breast epithelia but also
supports growth and differentiation of breast cancer, especially luminal subtypes. A principal …
supports growth and differentiation of breast cancer, especially luminal subtypes. A principal …
Identification of differentially expressed genes in breast tumors from African American compared with Caucasian women
LA Field, B Love, B Deyarmin, JA Hooke, CD Shriver… - Cancer, 2012 - Wiley Online Library
BACKGROUND: Breast tumors from African American women have less favorable pathological
characteristics and higher mortality rates than those of Caucasian women. Although …
characteristics and higher mortality rates than those of Caucasian women. Although …
[HTML][HTML] Low levels of Stat5a protein in breast cancer are associated with tumor progression and unfavorable clinical outcomes
…, TH Tran, MA Girondo, AL Rosenberg, JA Hooke… - Breast Cancer …, 2012 - Springer
Introduction Signal transducer and activator of transcripton-5a (Stat5a) and its close homologue,
Stat5b, mediate key physiological effects of prolactin and growth hormone in mammary …
Stat5b, mediate key physiological effects of prolactin and growth hormone in mammary …
Does breast tumor heterogeneity necessitate further immunohistochemical staining on surgical specimens?
LT Greer, M Rosman, WC Mylander, J Hooke… - Journal of the American …, 2013 - Elsevier
BACKGROUND: Prognostic and predictive tumor markers in breast cancer are most
commonly performed on core needle biopsies (CNB) of the primary tumor. Because treatment …
commonly performed on core needle biopsies (CNB) of the primary tumor. Because treatment …
High‐throughput proteomic analysis of human infiltrating ductal carcinoma of the breast
…, A Buchowiecka, C Arciero, H Brzeski, J Hooke… - …, 2003 - Wiley Online Library
Large‐scale proteomics will play a critical role in the rapid display, identification and
validation of new protein targets, and elucidation of the underlying molecular events that are …
validation of new protein targets, and elucidation of the underlying molecular events that are …
Methylobacterium mesophilicum Infection: Case Report and Literature Review of an Unusual Opportunistic Pathogen
…, JW Martin, M Hooke, J Hooke - Clinical Infectious …, 2000 - academic.oup.com
Methylobacterium mesophilicum is a methylotrophic, pink pigmented, gram-negative rod
that was initially isolated from environmental sources that is being increasingly reported as a …
that was initially isolated from environmental sources that is being increasingly reported as a …
[HTML][HTML] PCA-PAM50 improves consistency between breast cancer intrinsic and clinical subtyping reclassifying a subset of luminal A tumors as luminal B
PK Raj-Kumar, J Liu, JA Hooke, AJ Kovatich… - Scientific reports, 2019 - nature.com
The PAM50 classifier is widely used for breast tumor intrinsic subtyping based on gene
expression. Clinical subtyping, however, is based on immunohistochemistry assays of 3–4 …
expression. Clinical subtyping, however, is based on immunohistochemistry assays of 3–4 …
HYOU1/Orp150 expression in breast cancer
A Stojadinovic, JA Hooke, CD Shriver… - Medical Science …, 2007 - medscimonit.com
Background: Heat shock protein HYOU1, alternatively known as Orp150, plays an important
role in hypoxia/ischemia and angiogenesis. Preliminary studies demonstrated increased …
role in hypoxia/ischemia and angiogenesis. Preliminary studies demonstrated increased …