Challenges in the diagnosis of Parkinson's disease
Parkinson's disease is the second most common neurodegenerative disease and its
prevalence has been projected to double over the next 30 years. An accurate diagnosis of …
prevalence has been projected to double over the next 30 years. An accurate diagnosis of …
The zebrafish embryo model in environmental risk assessment—applications beyond acute toxicity testing
S Scholz, S Fischer, U Gündel, E Küster… - … science and pollution …, 2008 - Springer
… However, if alterations in gene expression are used as indicators or predictors of adverse
effects, the knowledge on the effect of gene expression for an organism’s health is of particular …
effects, the knowledge on the effect of gene expression for an organism’s health is of particular …
Zebrafish embryos as an alternative to animal experiments—A commentary on the definition of the onset of protected life stages in animal welfare regulations
… /s. Mean total duration of swimming corresponds to the time larvae spent swimming (with a
velocity of ≥0.20 cm/s) over a period of 300 s … of rest (within 300 s). Swimming was recorded …
velocity of ≥0.20 cm/s) over a period of 300 s … of rest (within 300 s). Swimming was recorded …
[PDF][PDF] A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
… to that of the Finnish ALS cohort (n = 22, representing 29.3% of the cohort), and the GGGGCC
repeat expansion was highly associated with FTD in the Finnish population (Fisher’s exact …
repeat expansion was highly associated with FTD in the Finnish population (Fisher’s exact …
Genome-wide association study reveals genetic risk underlying Parkinson's disease
…, D Berg, C Paisan-Ruiz, P Lichtner, SW Scholz… - Nature …, 2009 - nature.com
We performed a genome-wide association study (GWAS) in 1,713 individuals of European
ancestry with Parkinson's disease (PD) and 3,978 controls. After replication in 3,361 cases …
ancestry with Parkinson's disease (PD) and 3,978 controls. After replication in 3,361 cases …
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
Background Genome-wide association studies (GWAS) in Parkinson's disease have increased
the scope of biological knowledge about the disease over the past decade. We aimed to …
the scope of biological knowledge about the disease over the past decade. We aimed to …
[PDF][PDF] Exome sequencing reveals VCP mutations as a cause of familial ALS
Using exome sequencing, we identified a p.R191Q amino acid change in the valosin-containing
protein (VCP) gene in an Italian family with autosomal dominantly inherited amyotrophic …
protein (VCP) gene in an Italian family with autosomal dominantly inherited amyotrophic …
Determinants of market reactions to restatement announcements
ZV Palmrose, VJ Richardson, S Scholz - Journal of accounting and …, 2004 - Elsevier
We examine the market reaction to a sample of 403 restatements announced from 1995 to
1999. We document an average abnormal return of about −9 percent over a 2-day …
1999. We document an average abnormal return of about −9 percent over a 2-day …
A measurement of the π0, η and η′ electromagnetic form factors
…, D Lüers, H Oberlack, P Schacht, S Scholz… - Zeitschrift für Physik C …, 1991 - Springer
We present measurement of the π 0 γ * γ, ηγ * γ and η′γ * γ form factors. The π 0 -form
factor is for the first time observed in the space-like region. The transition form factor of the η-…
factor is for the first time observed in the space-like region. The transition form factor of the η-…
Auditor independence, non‐audit services, and restatements: Was the US government right?
…, ZV Palmrose, S Scholz - Journal of Accounting …, 2004 - Wiley Online Library
… This dependence might reduce the auditor’s willingness to challenge possible misstatement
of a client’s financial statements. The auditor’s lack of independence could result in an …
of a client’s financial statements. The auditor’s lack of independence could result in an …