The zebrafish embryo model in environmental risk assessment—applications beyond acute toxicity testing
S Scholz, S Fischer, U Gündel, E Küster… - … science and pollution …, 2008 - Springer
Background, aim, and scope The use of fish embryos is not regulated by current legislations
on animal welfare and is therefore considered as a refinement, if not replacement of animal …
on animal welfare and is therefore considered as a refinement, if not replacement of animal …
Zebrafish embryos as an alternative to animal experiments—A commentary on the definition of the onset of protected life stages in animal welfare regulations
Worldwide, the zebrafish has become a popular model for biomedical research and (eco)toxicology.
Particularly the use of embryos is receiving increasing attention, since they are …
Particularly the use of embryos is receiving increasing attention, since they are …
[HTML][HTML] Post-COVID-19-associated morbidity in children, adolescents, and adults: a matched cohort study including more than 157,000 individuals with COVID-19 in …
…, M Treskova-Schwarzbach, D Hertle, S Scholz… - PLoS …, 2022 - journals.plos.org
Background Long-term health sequelae of the Coronavirus Disease 2019 (COVID-19) are a
major public health concern. However, evidence on post-acute COVID-19 syndrome (post-…
major public health concern. However, evidence on post-acute COVID-19 syndrome (post-…
Benchmarking organic micropollutants in wastewater, recycled water and drinking water with in vitro bioassays
Thousands of organic micropollutants and their transformation products occur in water. Although
often present at low concentrations, individual compounds contribute to mixture effects. …
often present at low concentrations, individual compounds contribute to mixture effects. …
[HTML][HTML] Applying adverse outcome pathways (AOPs) to support integrated approaches to testing and assessment (IATA)
Chemical regulation is challenged by the large number of chemicals requiring assessment
for potential human health and environmental impacts. Current approaches are too resource …
for potential human health and environmental impacts. Current approaches are too resource …
[HTML][HTML] OECD validation study to assess intra-and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing
…, E Salinas, KE Schneider, S Scholz… - Regulatory Toxicology …, 2014 - Elsevier
The OECD validation study of the zebrafish embryo acute toxicity test (ZFET) for acute aquatic
toxicity testing evaluated the ZFET reproducibility by testing 20 chemicals at 5 different …
toxicity testing evaluated the ZFET reproducibility by testing 20 chemicals at 5 different …
[HTML][HTML] Pre-existing health conditions and severe COVID-19 outcomes: an umbrella review approach and meta-analysis of global evidence
…, A Borodova, K Karimi, J Koch, T Nygren, S Scholz… - BMC medicine, 2021 - Springer
Background This study applies an umbrella review approach to summarise the global evidence
on the risk of severe COVID-19 outcomes in patients with pre-existing health conditions. …
on the risk of severe COVID-19 outcomes in patients with pre-existing health conditions. …
[HTML][HTML] Efficacy and effectiveness of COVID-19 vaccines against SARS-CoV-2 infection: interim results of a living systematic review, 1 January to 14 May 2021
…, W Külper-Schiek, A Pilic, S Reda, S Scholz… - …, 2021 - eurosurveillance.org
Evidence on COVID-19 vaccine efficacy/effectiveness (VE) in preventing asymptomatic
SARS-CoV-2 infections is needed to guide public health recommendations for vaccinated people…
SARS-CoV-2 infections is needed to guide public health recommendations for vaccinated people…
The role of behavioral ecotoxicology in environmental protection
For decades, we have known that chemicals affect human and wildlife behavior. Moreover,
due to recent technological and computational advances, scientists are now increasingly …
due to recent technological and computational advances, scientists are now increasingly …
Molecular biomarkers of endocrine disruption in small model fish
S Scholz, I Mayer - Molecular and cellular endocrinology, 2008 - Elsevier
A wide range of environmental contaminants can interfere with hormonal regulation in
vertebrates. These endocrine disrupting chemicals (EDCs) are of high relevance for human and …
vertebrates. These endocrine disrupting chemicals (EDCs) are of high relevance for human and …